Orthopädische Gelenk-Klinik

Orthopädische Gelenk-Klinik

Alte Bundesstr. 58, 79194 Gundelfingen

Tel: (0761) 55 77 58 0

patienten@gelenk-klinik.de

Osteoarthritis and articular cartilage use, disuse, and abuse: experimental studies.

TitelOsteoarthritis and articular cartilage use, disuse, and abuse: experimental studies.
Publication TypeJournal Article
Year of Publication1995
AuthorsBuckwalter, JA
JournalThe Journal of rheumatology. Supplement
Volume43
Pagination13-5
Date Published1995 Feb
ISSN0380-0903
SchlüsselwörterArthrose, Arthrose-Risiko
Abstract Recent investigations have distinguished 3 different patterns of articular cartilage use that have different consequences: normal use, marked decrease use (disuse), and use that damages the tissue (abuse). In vitro cyclic loading of cartilage in the physiologic range stimulates matrix synthesis. In vivo, lifelong moderate and probably even strenuous joint use does not cause cartilage degeneration in normal animal joints, i.e., joints with normal articular surfaces, alignment, stability, innervation, and muscle control. In contrast, static loading or the absence of loading causes matrix degradation and eventually loss of joint function. Abuse of normal joints by single or repetitive impact loads can lead to progressive degeneration of the articular surface. Normal use of abnormal joints, in particular joints with incongruous articular surfaces, malalignment, instability, or disturbances of joint or muscle innervation may also increase the risk of degenerative joint disease.
Alternate JournalJ Rheumatol Suppl
Full Text
PubMed ID7752117
Folgen Sie der Gelenk-Klinik auf Facebook oder Twitter

FOCUS-Empfehlung

Focus Empfehlung zu Orthopäden im Freiburg Gundelfingen

Bitte ein Gelenk wählen

Anatomische Struktur
Schulterschmerzen Ellenbogenschmerzen Hand und Handgelenk Huefte Wirbelsäule Hand Fuss Sprunkggelenk und Schmerzen im Knöchel Knieschmerzen und Schmerzen im Knöchel

Jobportal des Gelenk-Klinik MVZ

Wir haben Spaß an unserer Arbeit und möchten dich daran teilhaben lassen. Für unsere Klinikerweiterung in 2019 suchen wir daher Verstärkung: